CDKN1B Break Apart FISH Probe
Empire Genomics’ CDKN1B Break Apart FISH Probe is designed to flank the CDKN1B gene and is typically used for detecting CDKN1B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDKN1BBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-GORE | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-GROR | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| CDKN1BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: CDKN1B
Gene Name: Cyclin Dependent Kinase Inhibitor 1B
Chromosome: CHR12: 12870301-12875305
Locus: 12p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDKN1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDKN1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping