CDK6 FISH Probe
The CDK6 FISH probe is designed to hybridize to the CDK6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDK6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDK6-20-RE | 20 (40 μL) | 200 μL |  |
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| CDK6-20-GO | 20 (40 μL) | 200 μL |  |
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| CDK6-20-GR | 20 (40 μL) | 200 μL |  |
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| CDK6-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDK6-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDK6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: CDK6
Gene Name: Cyclin Dependent Kinase 6
Chromosome: CHR7: 92234234-92465941
Locus: 7q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDK6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDK6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping