CDK2AP1 Break Apart FISH Probe
Empire Genomics’ CDK2AP1 Break Apart FISH Probe is designed to flank the CDK2AP1 gene and is typically used for detecting CDK2AP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK2AP1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| CDK2AP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: CDK2AP1
Gene Name: Cyclin Dependent Kinase 2 Associated Protein 1
Chromosome: CHR12: 123745539-123756687
Locus: 12q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDK2AP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDK2AP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping