CDHB FISH Probe
The CDHB FISH probe is designed to hybridize to the CDHB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CDH12-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CDH12-20-RE | 20 (40 μL) | 200 μL | ||
CDH12-20-GO | 20 (40 μL) | 200 μL | ||
CDH12-20-GR | 20 (40 μL) | 200 μL | ||
CDH12-20-AQ | 20 (40 μL) | 200 μL | ||
CDH12-20-DIG | 20 (40 μL) | 200 μL | ||
CDH12-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CDH12
Gene Name: Cadherin 12
Chromosome: CHR5: 21750972-22853731
Locus: 5p14.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDHB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDH12-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping