CDH3 FISH Probe
The CDH3 FISH probe is designed to hybridize to the CDH3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CDH3-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CDH3-20-RE | 20 (40 μL) | 200 μL | ||
CDH3-20-GO | 20 (40 μL) | 200 μL | ||
CDH3-20-GR | 20 (40 μL) | 200 μL | ||
CDH3-20-AQ | 20 (40 μL) | 200 μL | ||
CDH3-20-DIG | 20 (40 μL) | 200 μL | ||
CDH3-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CDH3
Gene Name: Cadherin 3
Chromosome: CHR16: 68678150-68732957
Locus: 16q22.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDH3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping