CDH1 FISH Probe
The CDH1 FISH probe is designed to hybridize to the CDH1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDH1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDH1-20-RE | 20 (40 μL) | 200 μL |  |
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| CDH1-20-GO | 20 (40 μL) | 200 μL |  |
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| CDH1-20-GR | 20 (40 μL) | 200 μL |  |
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| CDH1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDH1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDH1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CDH1
Gene Name: Cadherin 1
Chromosome: CHR16: 68771194-68869444
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDH1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDH1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping