CDC42 Break Apart FISH Probe
Empire Genomics’ CDC42 Break Apart FISH Probe is designed to flank the CDC42 gene and is typically used for detecting CDC42 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDC42BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDC42BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CDC42BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CDC42BA-20-GORE | 20 (40 μL) | 200 μL |
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| CDC42BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CDC42BA-20-GROR | 20 (40 μL) | 200 μL |
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| CDC42BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CDC42BA-20-REGO | 20 (40 μL) | 200 μL |
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| CDC42BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Gene Details
Gene Symbol: CDC42
Gene Name: Cell Division Cycle 42
Chromosome: CHR1: 22379119-22419436
Locus: 1p36.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDC42 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDC42-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping