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CD59 FISH Probe

The CD59 FISH probe is designed to hybridize to the CD59 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
CD59-20-OR  (Standard Design) 20 (40 μL) 200 μL
CD59-20-RE 20 (40 μL) 200 μL
CD59-20-GO 20 (40 μL) 200 μL
CD59-20-GR 20 (40 μL) 200 μL
CD59-20-AQ 20 (40 μL) 200 μL
CD59-20-DIG 20 (40 μL) 200 μL
CD59-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CD59

Gene Name: CD59 Molecule (CD59 Blood Group)

Chromosome: CHR11: 33724555-33758025

Locus: 11p13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CD59 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CD59-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping