CD46 FISH Probe
The CD46 FISH probe is designed to hybridize to the CD46 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD46-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CD46-20-RE | 20 (40 μL) | 200 μL |  |
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| CD46-20-GO | 20 (40 μL) | 200 μL |  |
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| CD46-20-GR | 20 (40 μL) | 200 μL |  |
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| CD46-20-AQ | 20 (40 μL) | 200 μL |  |
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| CD46-20-DIG | 20 (40 μL) | 200 μL |  |
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| CD46-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: CD46
Gene Name: CD46 Molecule
Chromosome: CHR1: 207925382-207968861
Locus: 1q32.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD46 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD46-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping