CD268 FISH Probe
The CD268 FISH probe is designed to hybridize to the CD268 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TNFRSF13C-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-RE | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-GO | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-GR | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-AQ | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-DIG | 20 (40 μL) | 200 μL | ||
TNFRSF13C-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TNFRSF13C
Gene Name: TNF Receptor Superfamily Member 13C
Chromosome: CHR22: 42321035-42322821
Locus: 22q13.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: CD268 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFRSF13C-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping