CD207 FISH Probe
The CD207 FISH probe is designed to hybridize to the CD207 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CD207-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CD207-20-RE | 20 (40 μL) | 200 μL | ||
CD207-20-GO | 20 (40 μL) | 200 μL | ||
CD207-20-GR | 20 (40 μL) | 200 μL | ||
CD207-20-AQ | 20 (40 μL) | 200 μL | ||
CD207-20-DIG | 20 (40 μL) | 200 μL | ||
CD207-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: CD207
Gene Name: CD207 Molecule
Chromosome: CHR2: 71057342-71062953
Locus: 2p13.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD207 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD207-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping