CD174 FISH Probe
The CD174 FISH probe is designed to hybridize to the CD174 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FUT3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FUT3-20-RE | 20 (40 μL) | 200 μL |  |
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| FUT3-20-GO | 20 (40 μL) | 200 μL |  |
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| FUT3-20-GR | 20 (40 μL) | 200 μL |  |
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| FUT3-20-AQ | 20 (40 μL) | 200 μL |  |
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| FUT3-20-DIG | 20 (40 μL) | 200 μL |  |
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| FUT3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FUT3
Gene Name: Fucosyltransferase 3 (Lewis Blood Group)
Chromosome: CHR19: 5842898-5851485
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD174 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FUT3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping