CD16 FISH Probe
The CD16 FISH probe is designed to hybridize to the CD16 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FCGR3A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-RE | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-GO | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-GR | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-AQ | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-DIG | 20 (40 μL) | 200 μL |  |
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| FCGR3A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FCGR3A
Gene Name: Fc Fragment Of IgG Receptor IIIa
Chromosome: CHR1: 161511550-161520413
Locus: 1q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD16 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FCGR3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping