CCR-7 FISH Probe
The CCR-7 FISH probe is designed to hybridize to the CCR-7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCR7-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR7-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR7-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR7-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCR7-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCR7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Details
Gene Symbol: CCR7
Gene Name: C-C Motif Chemokine Receptor 7
Chromosome: CHR17: 38710021-38721736
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CCR-7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCR7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping