CCNH FISH Probe
The CCNH FISH probe is designed to hybridize to the CCNH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCNH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCNH-20-RE | 20 (40 μL) | 200 μL |  |
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| CCNH-20-GO | 20 (40 μL) | 200 μL |  |
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| CCNH-20-GR | 20 (40 μL) | 200 μL |  |
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| CCNH-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCNH-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCNH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
Gene Details
Gene Symbol: CCNH
Gene Name: Cyclin H
Chromosome: CHR5: 86690078-86708850
Locus: 5q14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CCNH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCNH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping