CCNA1-1 FISH Probe
The CCNA1-1 FISH probe is designed to hybridize to the CCNA1-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CCNA1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CCNA1-20-RE | 20 (40 μL) | 200 μL | ||
CCNA1-20-GO | 20 (40 μL) | 200 μL | ||
CCNA1-20-GR | 20 (40 μL) | 200 μL | ||
CCNA1-20-AQ | 20 (40 μL) | 200 μL | ||
CCNA1-20-DIG | 20 (40 μL) | 200 μL | ||
CCNA1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CCNA1
Gene Name: Cyclin A1
Chromosome: CHR13: 37005966-37017019
Locus: 13q13.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CCNA1-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCNA1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping