CBSL Break Apart FISH Probe
Empire Genomics’ CBSL Break Apart FISH Probe is designed to flank the CBSL gene and is typically used for detecting CBSL rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CBSLBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CBSLBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CBSLBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CBSLBA-20-GORE | 20 (40 μL) | 200 μL |
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| CBSLBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CBSLBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CBSLBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CBSLBA-20-REGO | 20 (40 μL) | 200 μL |
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| CBSLBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: CBS
Gene Name: Cystathionine-beta-synthase
Chromosome: CHR21: 44473300-44496472
Locus: 21q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CBSL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CBS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping