CBLB FISH Probe
The CBLB FISH probe is designed to hybridize to the CBLB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CBLB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CBLB-20-RE | 20 (40 μL) | 200 μL |  |
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| CBLB-20-GO | 20 (40 μL) | 200 μL |  |
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| CBLB-20-GR | 20 (40 μL) | 200 μL |  |
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| CBLB-20-AQ | 20 (40 μL) | 200 μL |  |
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| CBLB-20-DIG | 20 (40 μL) | 200 μL |  |
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| CBLB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: CBLB
Gene Name: Cbl Proto-oncogene B
Chromosome: CHR3: 105377108-105587887
Locus: 3q13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CBLB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CBLB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping