CAV1 FISH Probe
The CAV1 FISH probe is designed to hybridize to the CAV1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAV1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CAV1-20-RE | 20 (40 μL) | 200 μL |  |
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| CAV1-20-GO | 20 (40 μL) | 200 μL |  |
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| CAV1-20-GR | 20 (40 μL) | 200 μL |  |
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| CAV1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CAV1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CAV1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: CAV1
Gene Name: Caveolin 1
Chromosome: CHR7: 116164838-116201239
Locus: 7q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAV1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAV1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping