CASP14 Break Apart FISH Probe
Empire Genomics’ CASP14 Break Apart FISH Probe is designed to flank the CASP14 gene and is typically used for detecting CASP14 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASP14BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CASP14BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CASP14
Gene Name: Caspase 14
Chromosome: CHR19: 15160290-15169103
Locus: 19p13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CASP14 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CASP14-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping