CASP10 Break Apart FISH Probe
Empire Genomics’ CASP10 Break Apart FISH Probe is designed to flank the CASP10 gene and is typically used for detecting CASP10 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CASP10BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CASP10BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CASP10BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CASP10BA-20-GORE | 20 (40 μL) | 200 μL |
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| CASP10BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CASP10BA-20-GROR | 20 (40 μL) | 200 μL |
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| CASP10BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CASP10BA-20-REGO | 20 (40 μL) | 200 μL |
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| CASP10BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Gene Details
Gene Symbol: CASP10
Gene Name: Caspase 10
Chromosome: CHR2: 202047620-202094129
Locus: 2q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CASP10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CASP10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping