CASP1 Break Apart FISH Probe
Empire Genomics’ CASP1 Break Apart FISH Probe is designed to flank the CASP1 gene and is typically used for detecting CASP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CASP1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CASP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CASP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CASP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| CASP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CASP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CASP1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CASP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| CASP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: CASP1
Gene Name: Caspase 1
Chromosome: CHR11: 104896236-104972158
Locus: 11q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CASP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CASP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping