CASP-3 FISH Probe
The CASP-3 FISH probe is designed to hybridize to the CASP-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASP3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CASP3-20-RE | 20 (40 μL) | 200 μL |  |
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| CASP3-20-GO | 20 (40 μL) | 200 μL |  |
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| CASP3-20-GR | 20 (40 μL) | 200 μL |  |
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| CASP3-20-AQ | 20 (40 μL) | 200 μL |  |
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| CASP3-20-DIG | 20 (40 μL) | 200 μL |  |
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| CASP3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: CASP3
Gene Name: Caspase 3
Chromosome: CHR4: 185548849-185570629
Locus: 4q35.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CASP-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CASP3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping