CAS1 FISH Probe
The CAS1 FISH probe is designed to hybridize to the CAS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCAR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-RE | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-GO | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-GR | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| BCAR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: BCAR1
Gene Name: BCAR1, Cas Family Scaffolding Protein
Chromosome: CHR16: 75262927-75301951
Locus: 16q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CAS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCAR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping