CARMA1 FISH Probe
The CARMA1 FISH probe is designed to hybridize to the CARMA1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CARD11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CARD11-20-RE | 20 (40 μL) | 200 μL |  |
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| CARD11-20-GO | 20 (40 μL) | 200 μL |  |
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| CARD11-20-GR | 20 (40 μL) | 200 μL |  |
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| CARD11-20-AQ | 20 (40 μL) | 200 μL |  |
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| CARD11-20-DIG | 20 (40 μL) | 200 μL |  |
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| CARD11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CARD11
Gene Name: Caspase Recruitment Domain Family Member 11
Chromosome: CHR7: 2945709-3083509
Locus: 7p22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CARMA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CARD11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping