CARDINAL FISH Probe
The CARDINAL FISH probe is designed to hybridize to the CARDINAL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CARD8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-RE | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-GO | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-GR | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CARD8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
Gene Details
Gene Symbol: CARD8
Gene Name: Caspase Recruitment Domain Family Member 8
Chromosome: CHR19: 48711342-48759203
Locus: 19q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CARDINAL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CARD8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping