CALM2 FISH Probe
The CALM2 FISH probe is designed to hybridize to the CALM2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CALM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CALM2-20-RE | 20 (40 μL) | 200 μL |  |
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| CALM2-20-GO | 20 (40 μL) | 200 μL |  |
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| CALM2-20-GR | 20 (40 μL) | 200 μL |  |
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| CALM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| CALM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| CALM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Gene Details
Gene Symbol: CALM2
Gene Name: Calmodulin 2
Chromosome: CHR2: 47387220-47403740
Locus: 2p21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CALM2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CALM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping