CALDAG-GE FISH Probe
The CALDAG-GE FISH probe is designed to hybridize to the CALDAG-GE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RASGRP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
RASGRP1-20-RE | 20 (40 μL) | 200 μL | ||
RASGRP1-20-GO | 20 (40 μL) | 200 μL | ||
RASGRP1-20-GR | 20 (40 μL) | 200 μL | ||
RASGRP1-20-AQ | 20 (40 μL) | 200 μL | ||
RASGRP1-20-DIG | 20 (40 μL) | 200 μL | ||
RASGRP1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RASGRP1
Gene Name: RAS Guanyl Releasing Protein 1
Chromosome: CHR15: 38780301-38857007
Locus: 15q14
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CALDAG-GE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASGRP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping