CAGH1A FISH Probe
The CAGH1A FISH probe is designed to hybridize to the CAGH1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZNF384-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-RE | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-GO | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-GR | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-AQ | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-DIG | 20 (40 μL) | 200 μL |  |
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| ZNF384-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
Gene Details
Gene Symbol: ZNF384
Gene Name: Zinc Finger Protein 384
Chromosome: CHR12: 6775642-6798738
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAGH1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ZNF384-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping