CAD Break Apart FISH Probe
Empire Genomics’ CAD Break Apart FISH Probe is designed to flank the CAD gene and is typically used for detecting CAD rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CADBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CADBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CADBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CADBA-20-GORE | 20 (40 μL) | 200 μL |
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| CADBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CADBA-20-GROR | 20 (40 μL) | 200 μL |
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| CADBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CADBA-20-REGO | 20 (40 μL) | 200 μL |
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| CADBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: CAD
Gene Name: Carbamoyl-phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase
Chromosome: CHR2: 27440257-27466654
Locus: 2p23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping