C88279 FISH Probe
The C88279 FISH probe is designed to hybridize to the C88279 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF34-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RNF34-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF34-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF34-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF34-20-AQ | 20 (40 μL) | 200 μL |  |
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| RNF34-20-DIG | 20 (40 μL) | 200 μL |  |
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| RNF34-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: RNF34
Gene Name: Ring Finger Protein 34
Chromosome: CHR12: 121837901-121862155
Locus: 12q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C88279 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNF34-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping