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C79664 FISH Probe

The C79664 FISH probe is designed to hybridize to the C79664 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CPSF4-20-OR  (Standard Design) 20 (40 μL) 200 μL
CPSF4-20-RE 20 (40 μL) 200 μL
CPSF4-20-GO 20 (40 μL) 200 μL
CPSF4-20-GR 20 (40 μL) 200 μL
CPSF4-20-AQ 20 (40 μL) 200 μL
CPSF4-20-DIG 20 (40 μL) 200 μL
CPSF4-20-BIO 20 (40 μL) 200 μL

Gene Summary

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CPSF4

Gene Name: Cleavage And Polyadenylation Specific Factor 4

Chromosome: CHR7: 99036562-99054996

Locus: 7q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: C79664 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CPSF4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping