C76747 FISH Probe
The C76747 FISH probe is designed to hybridize to the C76747 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-RE | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-GO | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-GR | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-AQ | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-DIG | 20 (40 μL) | 200 μL |  |
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| ARHGEF3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ARHGEF3
Gene Name: Rho Guanine Nucleotide Exchange Factor 3
Chromosome: CHR3: 56761445-57113336
Locus: 3p14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C76747 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARHGEF3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping