C5 Break Apart FISH Probe
Empire Genomics’ C5 Break Apart FISH Probe is designed to flank the C5 gene and is typically used for detecting C5 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| C5BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| C5BA-20-AQOR | 20 (40 μL) | 200 μL |
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| C5BA-20-GOGR | 20 (40 μL) | 200 μL |
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| C5BA-20-GORE | 20 (40 μL) | 200 μL |
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| C5BA-20-GRGO | 20 (40 μL) | 200 μL |
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| C5BA-20-GRRE | 20 (40 μL) | 200 μL |
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| C5BA-20-ORGR | 20 (40 μL) | 200 μL |
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| C5BA-20-REGO | 20 (40 μL) | 200 μL |
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| C5BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: C5
Gene Name: Complement C5
Chromosome: CHR9: 123714613-123812554
Locus: 9q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping