C5 FISH Probe
The C5 FISH probe is designed to hybridize to the C5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| C5-20-RE | 20 (40 μL) | 200 μL |  |
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| C5-20-GO | 20 (40 μL) | 200 μL |  |
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| C5-20-GR | 20 (40 μL) | 200 μL |  |
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| C5-20-AQ | 20 (40 μL) | 200 μL |  |
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| C5-20-DIG | 20 (40 μL) | 200 μL |  |
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| C5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: C5
Gene Name: Complement C5
Chromosome: CHR9: 123714613-123812554
Locus: 9q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping