C3 FISH Probe
The C3 FISH probe is designed to hybridize to the C3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| C3-20-RE | 20 (40 μL) | 200 μL |  |
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| C3-20-GO | 20 (40 μL) | 200 μL |  |
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| C3-20-GR | 20 (40 μL) | 200 μL |  |
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| C3-20-AQ | 20 (40 μL) | 200 μL |  |
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| C3-20-DIG | 20 (40 μL) | 200 μL |  |
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| C3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: C3
Gene Name: Complement C3
Chromosome: CHR19: 6677845-6720662
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping