C2-PI3K FISH Probe
The C2-PI3K FISH probe is designed to hybridize to the C2-PI3K gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIK3C2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-RE | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-GO | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-GR | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| PIK3C2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PIK3C2B
Gene Name: Phosphatidylinositol-4-phosphate 3-kinase Catalytic Subunit Type 2 Beta
Chromosome: CHR1: 204391757-204459474
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C2-PI3K FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PIK3C2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping