C-C CKR-3 FISH Probe
The C-C CKR-3 FISH probe is designed to hybridize to the C-C CKR-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCR3-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR3-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR3-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR3-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCR3-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCR3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: CCR3
Gene Name: C-C Motif Chemokine Receptor 3
Chromosome: CHR3: 46283871-46308197
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C-C CKR-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCR3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping