C-C CKR-10 FISH Probe
The C-C CKR-10 FISH probe is designed to hybridize to the C-C CKR-10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCR10-20-RE | 20 (40 μL) | 200 μL |  |
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| CCR10-20-GO | 20 (40 μL) | 200 μL |  |
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| CCR10-20-GR | 20 (40 μL) | 200 μL |  |
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| CCR10-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCR10-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCR10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
Gene Details
Gene Symbol: CCR10
Gene Name: C-C Motif Chemokine Receptor 10
Chromosome: CHR17: 40831419-40833845
Locus: 17q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C-C CKR-10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCR10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping