BTKI FISH Probe
The BTKI FISH probe is designed to hybridize to the BTKI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IBTK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IBTK-20-RE | 20 (40 μL) | 200 μL |  |
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| IBTK-20-GO | 20 (40 μL) | 200 μL |  |
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| IBTK-20-GR | 20 (40 μL) | 200 μL |  |
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| IBTK-20-AQ | 20 (40 μL) | 200 μL |  |
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| IBTK-20-DIG | 20 (40 μL) | 200 μL |  |
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| IBTK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: IBTK
Gene Name: Inhibitor Of Bruton Tyrosine Kinase
Chromosome: CHR6: 82879955-82957448
Locus: 6q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BTKI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IBTK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping