BRE1A FISH Probe
The BRE1A FISH probe is designed to hybridize to the BRE1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF20-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RNF20-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF20-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF20-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF20-20-AQ | 20 (40 μL) | 200 μL |  |
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| RNF20-20-DIG | 20 (40 μL) | 200 μL |  |
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| RNF20-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
Gene Details
Gene Symbol: RNF20
Gene Name: Ring Finger Protein 20
Chromosome: CHR9: 104296132-104325626
Locus: 9q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BRE1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNF20-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping