BRD2-IT1 FISH Probe
The BRD2-IT1 FISH probe is designed to hybridize to the BRD2-IT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
BRD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
BRD2-20-RE | 20 (40 μL) | 200 μL | ||
BRD2-20-GO | 20 (40 μL) | 200 μL | ||
BRD2-20-GR | 20 (40 μL) | 200 μL | ||
BRD2-20-AQ | 20 (40 μL) | 200 μL | ||
BRD2-20-DIG | 20 (40 μL) | 200 μL | ||
BRD2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: BRD2
Gene Name: Bromodomain Containing 2
Chromosome: CHR6_ssto_hap7: 4367204-4430060
Locus: 6p21.32
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BRD2-IT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BRD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping