SEARCH OUR PRODUCT CATALOG

BRCA2 FISH Probe

The BRCA2 FISH probe is designed to hybridize to the BRCA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
BRCA2-20-OR  (Standard Design) 20 (40 μL) 200 μL
BRCA2-20-RE 20 (40 μL) 200 μL
BRCA2-20-GO 20 (40 μL) 200 μL
BRCA2-20-GR 20 (40 μL) 200 μL
BRCA2-20-AQ 20 (40 μL) 200 μL
BRCA2-20-DIG 20 (40 μL) 200 μL
BRCA2-20-BIO 20 (40 μL) 200 μL

Gene Summary

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]

Gene Details

Gene Symbol: BRCA2

Gene Name: BRCA2, DNA Repair Associated

Chromosome: CHR13: 32889616-32973809

Locus: 13q13.1

Gene Diseases

The BRCA2 gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
49,XXXXX Syndrome
Aagenaes Syndrome
Abderhalden-Kaufmann-Lignac Syndrome
Abrikosov's Tumor
Achard Syndrome
Achard-Thiers Syndrome
Acquired Hypoprothrombinemia
Acrocephalopolysyndactyly Type II
Acrokeratoderma, Hereditary Papulotranslucent
Acrootoocular Syndrome
Acrorenal Syndrome
Acrorenal Syndrome Recessive
Adactylia, Unilateral
Adenocarcinoid Tumor
Adenocarcinoma
Adrenocortical Carcinoma
Adrenocortical Carcinoma, Hereditary
Akaba Hayasaka Syndrome
Akesson Syndrome
Alcohol Fetopathy
ALCOHOL SENSITIVITY, ACUTE
Aloi Tomasini Isaia Syndrome
Alpha-Fetoprotein Deficiency
Alsing Syndrome
Ameloonychohypohidrotic Syndrome
Androblastoma Of Ovary
Anemia
Anemia, X-Linked, Without Thrombocytopenia
Angioedemas, Hereditary
Angiolipomatosis, Familial
Ansell Bywaters Elderking Syndrome
Arakawa Syndrome 2
AREDYLD Syndrome
Arima Syndrome
Astrocytoma
Asymptomatic Diseases
Ataxia
Ataxia Telangiectasia
Ataxia-Microcephaly-Cataract Syndrome
Ataxia-Telangiectasia Variant
Athrombia, Essential
Atresia Of Small Intestine
Aughton Syndrome
Ayazi Syndrome
Azoospermia
BADS Syndrome
Baetz-Greenwalt Syndrome
Bagatelle Cassidy Syndrome
Bangstad Syndrome
Bankart Lesions
Banki Syndrome
Banti's Syndrome
Basal Cell Carcinoma, Multiple
Basaran Yilmaz Syndrome
Bassoe Syndrome
Bazopoulou Kyrkanidou Syndrome
Beardwell Syndrome
Beemer Ertbruggen Syndrome
Bellini Chiumello Rimoldi Syndrome
Biemond Syndrome II
Bipolar Disorder
Blepharo-cheilo-dontic Syndrome
Blount Disease
Body Weight
Boerhaave Syndrome
Bone Anteversion
Bone Retroversion
Bonneau Syndrome
Boudhina Yedes Khiari Syndrome
Brachioskeletogenital Syndrome
Brachymesophalangy 2 And 5
Breast Cancer, Familial
Breast Cancer, Familial Male
Breast Carcinoma In Situ
Breast Neoplasms
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 3
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 4
Broad-Betalipoproteinemia
Brunoni Syndrome
CAHMR Syndrome
Calabro Syndrome
CAMFAK Syndrome
Campomelia Cumming Type
Cancer
CANOMAD Syndrome
Cantalamessa Baldini Ambrosi Syndrome
Carcinogenesis
Carcinoma
Carcinoma In Situ
Cardiocranial Syndrome
Cardiotoxicity
Cardiovascular Diseases
Carrington Syndrome
Cataract
CATARACT 13 WITH ADULT I PHENOTYPE
CATARACT 15, MULTIPLE TYPES
CATARACT 16, MULTIPLE TYPES
CATARACT 19, MULTIPLE TYPES
CATARACT 20, MULTIPLE TYPES
CATARACT 23, MULTIPLE TYPES
CATARACT 3, MULTIPLE TYPES
CATARACT 32, MULTIPLE TYPES
CATARACT 36
CATARACT 38
CATARACT 39, MULTIPLE TYPES
CATARACT 4, MULTIPLE TYPES
CATARACT 41
CATARACT 42
CATARACT 43
CATARACT 44
CATARACT 45
CATARACT 6, MULTIPLE TYPES
Cataract, Autosomal Dominant
Cataract, Autosomal Dominant Nuclear
Cataract, Autosomal Dominant, Multiple Types 1
Cataract, Nuclear Progressive
Cataract, Nuclear Total
Cataract, Progressive Polymorphic Cortical
CATSHL Syndrome
Cerebelloparenchymal Disorder II
Cerebrooculonasal Syndrome
Chilaiditi Syndrome
Childhood Myocerebrohepatopathy Spectrum
Chromosomal Instability
Chromosome 14q, Partial Deletions
Chromosome 14q, Terminal Deletion
Chromosome 14q, Terminal Duplication
Chromosome Aberrations
Chromosome Duplication
CLAPO Syndrome
Cleidorhizomelic Syndrome
Collagenoma, Familial Cutaneous
Corneal Hypesthesia, Familial
Corneodermatoosseous Syndrome
Coxoauricular Syndrome
Cranioacrofacial Syndrome
Craniofaciofrontodigital Syndrome
Craniomicromelic Syndrome
Crome Syndrome
Cryofibrinogenemia, Familial Primary
Cryptotia, Familial
Curatolo Cilio Pessagno Syndrome
CUTANEOUS TELANGIECTASIA AND CANCER SYNDROME, FAMILIAL
D-glycericacidemia
Daentl Towsend Siegel Syndrome
Daish Hardman Lamont Syndrome
Daneman Davy Mancer Syndrome
Davenport Donlan Syndrome
Death
Deletion 13q Syndrome, Partial
Dermatoosteolysis Kirghizian Type
Devriendt Syndrome
Diabetes Mellitus
Dieterich's Disease
Digitorenocerebral Syndrome
Dimauro Disease
Disease
Disease Progression
Diseases
Drachtman Weinblatt Sitarz Syndrome
Embolism
Endometriosis
Esophageal Atresia
Esophageal Squamous Cell Carcinoma
Faciocardiomelic Syndrome
Faciocardiorenal Syndrome
Factor 8 Deficiency, Acquired
Fairbank Disease
Fallopian Tube Neoplasms
Familial Dermographism
Familial Hyperbeta- And Prebetalipoproteinemia
Familial Spinal Arachnoiditis
Familial Streblodactyly
Familial Wilms Tumor 2
Fanconi Anemia
Fanconi Anemia, Complementation Group N
FANCONI ANEMIA, COMPLEMENTATION GROUP P
FANCONI ANEMIA, COMPLEMENTATION GROUP Q
FANCONI ANEMIA, COMPLEMENTATION GROUP R
FANCONI ANEMIA, COMPLEMENTATION GROUP T
FANCONI ANEMIA, COMPLEMENTATION GROUP U
FANCONI ANEMIA, COMPLEMENTATION GROUP V
Fanconi Like Syndrome
Fistula
FLOTCH Syndrome
Flynn Aird Syndrome
Fountain Syndrome
Franceschini Vardeu Guala Syndrome
Freiberg's Disease
Frontoocular Syndrome
Furlong Syndrome
Furukawa Takagi Nakao Syndrome
Gastrocutaneous Syndrome
Gemignani Syndrome
GEMSS Syndrome
Genoa Syndrome
Genomic Instability
German Syndrome
Giacheti Syndrome
Gigantiform Cementoma, Familial
Glaucoma
Glaucoma Iridogoniodysplasia, Familial
Glioblastoma
Glioma
Glioma Of Brain, Familial
Gollop Coates Syndrome
GOMBO Syndrome
Granddad Syndrome
Grover's Disease
Grubben De Cock Borghgraef Syndrome
Gurrieri Sammito Bellussi Syndrome
Hadziselimovic Syndrome
Hagemoser Weinstein Bresnick Syndrome
Halal Syndrome
Hamanishi Ueba Tsuji Syndrome
Hamano Tsukamoto Syndrome
Hapnes Boman Skeie Syndrome
Hardikar Syndrome
Hereditary Breast And Ovarian Cancer Syndrome
Hereditary Koilonychia
Hereditary Spinal Ataxia
Herrmann Syndrome
Hersh Podruch Weisskopk Syndrome
Hooft Disease
Hordnes Engebretsen Knudtson Syndrome
Human Balantidiasis
Hunt's Syndrome
Hyperexplexia Hereditary
Hyperplasia
Hyperreninemic Hypoaldosteronism, Familial, 2
Hypersensitivity
Hypoadrenocorticism, Familial
Hypoglossia, Isolated
Hypoxia
Iida Kannari Syndrome
Immune Deficiency, Familial Variable
Infarction
Infertility
Inflammation
Inflammatory Breast Neoplasms
Insulin Resistance
Jagell Holmgren Hofer Syndrome
Juvenile Osteoporosis
Kaplan Plauchu Fitch Syndrome
Kaplowitz Bodurtha Syndrome
Karoshi Death
Kasabach-Merritt Syndrome
Kashani Strom Utley Syndrome
Katsantoni Papadakou Lagoyanni Syndrome
Kennerknecht Sorgo Oberhoffer Syndrome
Kleeblattschaedel Syndrome
Koone Rizzo Elias Syndrome
Kosztolanyi Syndrome
Krasnow Qazi Syndrome
Kuskokwim Disease
Kuzniecky Syndrome
Kyrle Disease
Lachiewicz Sibley Syndrome
Lacrimoauriculodentodigital Syndrome
Lambotte Syndrome
Lelis Syndrome
Lemierre Syndrome
Leukemia
Leukemia, Acute, X-Linked
Li-Fraumeni Syndrome
Li-Fraumeni Syndrome 2
Lymphoma
Lyngstadaas Syndrome
Malformations Of Cortical Development, Group I
Malformations Of Cortical Development, Group II
Malformations Of Cortical Development, Group III
Malignant Teratocarcinosarcoma
Malouf Syndrome
Manouvrier Syndrome
Marchiafava-Bignami Disease
Marsden Syndrome
Massa Casaer Ceulemans Syndrome
May-Thurner Syndrome
Medulloblastoma
Mehes Syndrome
Melanoma
Melanoma, Cutaneous Malignant
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 1
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 10
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 4
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 5
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 8
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9
Melhem Fahl Syndrome
Mengel Konigsmark Syndrome
Meralgia Paraesthetica, Familial
Merlob Grunebaum Reisner Syndrome
Meyenburg-Altherr-Uehlinger Syndrome
Microcephaly
Microcephaly Autosomal Dominant
Microtrauma, Physical
Mirizzi Syndrome
Mollica Pavone Antener Syndrome
MOMES Syndrome
Mononen Karnes Senac Syndrome
Morgellons Disease
Myocardial Infarction
Nasodigitoacoustic Syndrome
Nathalie Syndrome
Neoplasms
Neoplastic Cells, Circulating
Neurofaciodigitorenal Syndrome
Neurofibromatosis Type 5
Neurofibromatosis, Familial Spinal
Neurofibromatosis, Type 4, Of Riccardi
Neutropenia
Nevo Syndrome
Nicolau Syndrome
Nievergelt Syndrome
Nivelon Nivelon Mabille Syndrome
Oculoauriculofrontonasal Syndrome
Oculocerebrocutaneous Syndrome
Oculodental Syndrome Rutherfurd Syndrome
Oculootoradial Syndrome
Oculopalatocerebral Syndrome
Oculopalatoskeletal Syndrome
Oculorenocerebellar Syndrome
Oligosynaptic Infertility
Onat Syndrome
Onychotrichodysplasia And Neutropenia
OOCYTE MATURATION DEFECT 1
OOCYTE MATURATION DEFECT 2
Oroticaciduria 1
Oslam Syndrome
Osteoporosis
Osteosarcoma
Otoonychoperoneal Syndrome
Ovarian Neoplasms
Overweight
Pachydermodactyly, Familial
Pancreatic Cancer, Adult
Pancreatic Carcinoma, Familial
Pancreatic Lymphoma, Familial
Pancytopenia
Parental Death
Parotidomegaly, Hereditary Bilateral
Pascual Castroviejo Syndrome
Pashayan Syndrome
Passovoy Factor
Pavone Fiumara Rizzo Syndrome
Pechet Factor Deficiency
PHACE Association
Pilotto Syndrome
Piussan Lenaerts Mathieu Syndrome
Podder-Tolmie Syndrome
Polyploidy
Polythelia, Familial
Postthrombotic Syndrome
Preeyasombat Varavithya Syndrome
PREGNANCY LOSS, RECURRENT, SUSCEPTIBILITY TO, 1
PREGNANCY LOSS, RECURRENT, SUSCEPTIBILITY TO, 2
PREGNANCY LOSS, RECURRENT, SUSCEPTIBILITY TO, 3
Pregnancy, Cornual
Primary Dysautonomias
Propping Zerres Syndrome
Prostate Cancer, Familial
PROSTATE CANCER, HEREDITARY, 1
Prostate Cancer, Hereditary, 12
Prostate Cancer, Hereditary, 13
Prostate Cancer, Hereditary, 6
Prostate Cancer, Hereditary, 8
PROSTATE CANCER, HEREDITARY, X-LINKED 1
Prostatic Stromal Proliferation Of Uncertain Malignant Potential
Protein Aggregation, Pathological
Pseudoacromegaly With Severe Insulin Resistance
Pseudoaminopterin Syndrome
Pseudoangiomatous Stromal Hyperplasia
Pseudoarylsulfatase A Deficiency
Pseudotrisomy 13 Syndrome
Qazi Markouizos Syndrome
Radial Ray Deficiency, X-Linked
Radiation Sensitivity Chromosome Instability Syndrome, Autosomal Dominant
Rambaud Galian Syndrome
Ramer Ladda Syndrome
Reactive Angioendotheliomatosis
Recurrence
Reginato Schiapachasse Syndrome
Retinohepatoendocrinologic Syndrome
RHYNS Syndrome
Ribbing Disease
Richards-Rundle Syndrome
Rombo Syndrome
Rosselli-Gulienetti Syndrome
Rudiger Syndrome
Sakoda Complex
Salcedo Syndrome
Sammartino De Crecchio Syndrome
Sandifer Syndrome
Satoyoshi Syndrome
Schlegelberger Grote Syndrome
Schofer Beetz Bohl Syndrome
Scholte Syndrome
Schrander-Stumpel Theunissen Hulsmans Syndrome
Seaver Cassidy Syndrome
Sebaceous Tumors, Somatic
Seemanova Lesny Syndrome
Sener Syndrome
Shapiro Syndrome
Short Stature And Facioauriculothoracic Malformations
Short Stature, Idiopathic, Autosomal
Short Stature, Idiopathic, X-Linked
Silengo Lerone Pelizza Syndrome
Sillence Syndrome
Sohval Soffer Syndrome
Steinfeld Syndrome
Summitt Syndrome
SUNCT Syndrome
SUPPRESSOR OF TUMORIGENICITY 3
Susac Syndrome
Syndrome
Syringomas, Multiple
Tabatznik Syndrome
Tatsumi Factor Deficiency
Tetraploidy
Three M Syndrome 2
Thrombocytopenia
Tonoki Syndrome
Translocation, Genetic
Trichodental Syndrome
Trueb Burg Bottani Syndrome
Tsukahara Syndrome
Tucker Syndrome
Unilateral Breast Neoplasms
Upington Disease
Uterine Anomalies
Uterine Cervical Diseases
Uterine Retroversion
Velofacioskeletal Syndrome
Verloove-Vanhorick Brubakk Syndrome
Volcke Soekarman Syndrome
WAGR Syndrome
Walbaum Titran Durieux Crepin Syndrome
Waldmann Disease
Warburton Anyane Yeboa Syndrome
Warman Mulliken Hayward Syndrome
Waterborne Diseases
Weight Gain
Weight Loss
Weismann Netter Syndrome
Wilms Tumor
WILMS TUMOR 5
WILMS TUMOR 6
Wyburn Mason's Syndrome
Young McKeever Squier Syndrome
Young Syndrome
Yusho Disease
Zazam Sheriff Phillips Syndrome
Zechi-Ceide Syndrome
ZINC, ELEVATED PLASMA
Zlotogora-Ogur Syndrome
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: BRCA2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BRCA2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping