SEARCH OUR PRODUCT CATALOG

BRCA2 FISH Probe

The BRCA2 FISH probe is designed to hybridize to the BRCA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
BRCA2-20-OR  (Standard Design) 20 (40 μL) 200 μL
BRCA2-20-RE 20 (40 μL) 200 μL
BRCA2-20-GO 20 (40 μL) 200 μL
BRCA2-20-GR 20 (40 μL) 200 μL
BRCA2-20-AQ 20 (40 μL) 200 μL
BRCA2-20-DIG 20 (40 μL) 200 μL
BRCA2-20-BIO 20 (40 μL) 200 μL

Gene Summary

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]

Gene Details

Gene Symbol: BRCA2

Gene Name: BRCA2, DNA Repair Associated

Chromosome: CHR13: 32889616-32973809

Locus: 13q13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: BRCA2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BRCA2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping