BPGM FISH Probe
The BPGM FISH probe is designed to hybridize to the BPGM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BPGM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BPGM-20-RE | 20 (40 μL) | 200 μL |  |
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| BPGM-20-GO | 20 (40 μL) | 200 μL |  |
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| BPGM-20-GR | 20 (40 μL) | 200 μL |  |
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| BPGM-20-AQ | 20 (40 μL) | 200 μL |  |
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| BPGM-20-DIG | 20 (40 μL) | 200 μL |  |
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| BPGM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: BPGM
Gene Name: Bisphosphoglycerate Mutase
Chromosome: CHR7: 134331530-134364567
Locus: 7q33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BPGM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BPGM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping