BMPR2 Break Apart FISH Probe
Empire Genomics’ BMPR2 Break Apart FISH Probe is designed to flank the BMPR2 gene and is typically used for detecting BMPR2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BMPR2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-GORE | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-GROR | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-REGO | 20 (40 μL) | 200 μL |
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| BMPR2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BMPR2
Gene Name: Bone Morphogenetic Protein Receptor Type 2
Chromosome: CHR2: 203241049-203432474
Locus: 2q33.1-q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BMPR2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BMPR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping