BMPR-II FISH Probe
The BMPR-II FISH probe is designed to hybridize to the BMPR-II gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMPR2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-RE | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-GO | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-GR | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-AQ | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-DIG | 20 (40 μL) | 200 μL |  |
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| BMPR2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BMPR2
Gene Name: Bone Morphogenetic Protein Receptor Type 2
Chromosome: CHR2: 203241049-203432474
Locus: 2q33.1-q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BMPR-II FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BMPR2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping