BMI1 FISH Probe
The BMI1 FISH probe is designed to hybridize to the BMI1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BMI1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BMI1-20-RE | 20 (40 μL) | 200 μL |  |
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| BMI1-20-GO | 20 (40 μL) | 200 μL |  |
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| BMI1-20-GR | 20 (40 μL) | 200 μL |  |
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| BMI1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BMI1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BMI1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: BMI1
Gene Name: BMI1 Proto-oncogene, Polycomb Ring Finger
Chromosome: CHR10: 22610138-22620414
Locus: 10p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BMI1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BMI1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping