BLNK FISH Probe
The BLNK FISH probe is designed to hybridize to the BLNK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BLNK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BLNK-20-RE | 20 (40 μL) | 200 μL |  |
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| BLNK-20-GO | 20 (40 μL) | 200 μL |  |
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| BLNK-20-GR | 20 (40 μL) | 200 μL |  |
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| BLNK-20-AQ | 20 (40 μL) | 200 μL |  |
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| BLNK-20-DIG | 20 (40 μL) | 200 μL |  |
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| BLNK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: BLNK
Gene Name: B-cell Linker
Chromosome: CHR10: 97951454-98031333
Locus: 10q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BLNK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BLNK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping