BIN1 FISH Probe
The BIN1 FISH probe is designed to hybridize to the BIN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BIN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BIN1-20-RE | 20 (40 μL) | 200 μL |  |
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| BIN1-20-GO | 20 (40 μL) | 200 μL |  |
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| BIN1-20-GR | 20 (40 μL) | 200 μL |  |
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| BIN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BIN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BIN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: BIN1
Gene Name: Bridging Integrator 1
Chromosome: CHR2: 127805598-127864903
Locus: 2q14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BIN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BIN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping