BFNC2 FISH Probe
The BFNC2 FISH probe is designed to hybridize to the BFNC2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNQ3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: KCNQ3
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 3
Chromosome: CHR8: 133133104-133493004
Locus: 8q24.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BFNC2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNQ3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping